C3G (Cyanidin 3 Glucoside)

C3G (Cyanidin-3-Glucoside) is a naturally occurring plant pigment. It belongs to the class of anthocyanins known as flavonoids. Researchers have noticed that C3G is formed when the anthocyanidin is attached to a glucose molecule at the 3-position.

Preliminary studies suggest that C3G is responsible for the colors found in foods like berries, black rice, and purple corn. It generally provides foods with their red, purple, and blue shades. Additionally, researchers have found that C3G is water-soluble and it changes colour when its pH levels change.

C3G is currently studied for its potential to boost antioxidant protection, metabolic health, and cognitive function in preclinical models. A few studies have also observed C3G’s possible effects on inflammation control in experimental settings.

Chemical Properties

Working Mechanism of C3G (Cyanidin-3-Glucoside)

Below is the working mechanism of C3G (Cyanidin-3-Glucoside) as observed in different preclinical models.

1. Antioxidant Defense

In different research models, C3G has appeared to act as a powerful free radical scavenger. Preliminary studies have suggested that C3G may directly neutralize reactive oxygen species (ROS).

2. Inflammatory Pathway Control

C3G indirectly suppresses the activation of NF-κB, a key regulator of inflammation, after reducing the oxidative stress in research models.

This leads to lower production of pro-inflammatory cytokines (TNF-a, IL-6, IL-1B) and enzymes such as COX-2 and iNOS. As a result, chronic low-grade inflammation is reduced in experimental models.

3. Metabolic Regulation

It has been observed that C3G may activate AMPK (AMP-activated protein kinase). In various preclinical studies, researchers have noticed that AMPK activation may enhance glucose uptake. It may improve insulin sensitivity and promote fatty acid oxidation in research models.

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